MECANISMOS INVOLUCRADOS EN LA ACTIVIDAD ANTIOXIDANTE Y ANTIBACTERIANA DEL PROPÓLEOS

Autores/as

  • R D Vargas-Sánchez Centro de Investigación en Alimentación y Desarrollo, A.C.
  • G R Torrescano-Urrutia Centro de Investigación en Alimentación y Desarrollo, A.C.
  • A M Mendoza-Wilson Centro de Investigación en Alimentación y Desarrollo, A.C.
  • B Vallejo-Galland Centro de Investigación en Alimentación y Desarrollo, A.C.
  • E Acedo-Félix Centro de Investigación en Alimentación y Desarrollo, A.C.
  • J J SánchezEscalante Universidad de Sonora, DICTUS.
  • M C Peñalba-Garmendia MC Universidad de Sonora, DICTUS.
  • A Sánchez-Escalante Centro de Investigación en Alimentación y Desarrollo, A.C.

DOI:

https://doi.org/10.18633/bt.v16i1.31

Palabras clave:

propóleos, mecanismo antioxidante, antibacteriano, flavonoides.

Resumen

El propóleos es un producto elaborado por las abejas, que se caracteriza por poseer propiedades antioxidantes y antimicrobianas, las cuales son atribuidas a la presencia de compuestos polifenólicos, principalmente flavonoides. Estos compuestos son de bajo peso molecular y en su estructura química contienen un número variable de grupos hidroxilos. Varios investigadores han reportado que los mecanismos antioxidantes propuestos para estos grupos son mediante secuestro de radicales libres, o actuando como substrato para radicales, tales como superóxido e hidroxilo, y quelación de iones metálicos. Mientras que el mecanismo antimicrobiano involucra la inhibición de ácidos nucleicos y degradación de la membrana citoplasmática.

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Citas

Abd El Hady, F.K. y Hegazi, A.G. 2002. Egyptian propolis; 2 – Chemical composition, antiviral and antimicrobial activity of East Nile Delta propolis. Z. Zeitschrift für Naturforschung. 57: 386-391.

Bankova, V., Boudourova-Krasteva, G., Sforcin, M.J., Frete, X., Kujumgiev, A. y Maimoni-Rodella, R. 1999. Phytochemical evidence for the plant origin of Brazilian propolis from Sao Paulo state. Zeitschrift für Naturforschung. 54: 401-405.

Bankova V. 2009. Review: chemical diversity of propolis makes it a valuable source of new biologically active compounds. Journal of ApiProduct and ApiMedical Science. 1(2): 23–28.

Choi YM, Noh DO, Cho SY, Suh HJ, Kim KM, y Kim JM. 2006. Antioxidant and antimicrobial activities of propolis from several regions of Korea. LWT- Food Science and Technology. 39: 756-761.

Chopra, S., Pillai, K.K., Husain, S.Z. y Giri, D.K. 1995. Propolis protects against doxorubicin-induced myocardiopathy in rats.Experimental and Molecular Pathology. 62: 190-198.

Cos, P., Rajan, P., Vedernikova, I., Calomme, M., Pieters, L., Vlietinck, A.J., Augustyns, K., Haemers, A. y Berghe, D.V. 2002. In vitro antioxidant profile of phenolic acid derivatives. Free Radical Research. 36:711–716.

Cushnie, T.P.T. y Lamb, A.J. 2005a. Antimicrobial activity of flavonoids. International Journal of Antimicrobial Agents. 26:343-356.

Cushnie, T.P. y Lamb, A.J. 2005b. Detection of galangin-induced cytoplasmic membrane damage in Staphylococcus aureus by measuring potassium loss. Journal of Ethnopharmacology. 101: 243–248.

Das, N.P. y Pereira, T.A. 1990. Effects of flavonoids on thermal autoxidation of palm oil: structure-activity relationships. Journal of the American Oil Chemists’ Society. 76(4): 255-258.

Ergün, B.Ç., Çoban, T., Onurdag, F.K. y Banoglu, E. 2011. Synthesis, Antioxidant and Antimicrobial Evaluation of Simple Aromatic Esters of Ferulic Acid. Archives of Pharmacal Research. 34(8): 1251-1261.

Erkoc, S., Erkoc, F. y Keskin, N. 2003. Theoretical investigation of quercetin and its radicals isomers. Journal of Molecular Structure. TEOCHEM. 631:141-146.

Eumkeb, G., Siriwong, S. y Thumanu, K. 2012. Synergistic activity of luteolin and amoxicilin combination against resistant Escherichia coli and mode of action. Journal of Photochemistry and Photobiology. 117: 247 253.

FAO. 1996. Value-added products from beekeeping. Food and Agriculture Organization of the United Nations. Bulletin no. 124. Roma.

Farré, R., Frasquet, I., y Sánchez, A. 2004. El própolis y la salud. Ars Pharmaceutica. 45(1): 23-43.

Geckil, H., Ates, B., Durmaz, G., Erdogan, S. y Yilmaz, I. 2005. Antioxidant, free radical scavenging and metal chelating characteristics of propolis. American Journal of Biochemis-try and Biotechnology. 1(1): 27-31.

Kumazawa, S., Fujimoto, T. y Nakayama, T. 2004. Antioxidant activity and constituents of propolis collected in various areas of Japan. Food Science and Technology Research. 10 (1): 86–92.

Havsteen, B.H. 2002. The biochemistry and medical significance of flavonoids. Pharmacology and Therapeutics. 96: 67-202. Hilliard, J.J., Krause, H.M. y Bernstein, J.I. 1995. A comparison of active site binding of 4-quinolones and novel flavone gyrase inhibitors to DNA gyrase. Advances in Experimental Medicine and Biology. 390:59–69.

Ikigai, H., Nakae, T., Hara, Y. y Shimamura, T. 1993. Bactericidal catechins damage the lipid bilayer. Biochemical and Biophysica Acta. 1147: 132–6.

Irmak, M.K., Fadillioglu, E. y Sogut, S. 2003. Effects of caffeic acid phenethyl ester and alpha-tocopherol on reperfusion injury in rat brain. Cell Biochemistry and Function. 21: 283-289.

Jovanovic, S.V., Steenken, S., Tosic, M., Marjanovic, B. y Simic, M.G. 1994. Flavonoids as antioxidants. Journal of American Chemistry Society. 116: 4846-4851.

Kanaski, J., Aksenova, M., Stoyanova, A. y Butterfield D.A. 2002. Ferulic acid antioxidant protection against hydroxyl and peroxyl radical oxidation in synaptosomal and neuronal cell culture systems in vitro: Structure activity studies. The Journal of Nutritional Biochemistry. 13: 273–281.

Kroon, P.A. y Williamson, G. 1999. Hidroxycinnamates in plants and food: current and future perspective. Journal of Food Science and Agriculture. 79: 355-361.

Kumar-Maurya, D. y Asir-Devasagayam, T.P. 2010. Antioxidant and prooxidant nature of hydroxycinnamic acid derivatives ferulic and caffeic acids. Food and Chemical Toxicology. 48: 3369–3373.

Kumar, N., Anmad, K.K.M., Dang, R. y Husain, A. 2008. Antioxidant and antimicrobial activity of propolis from Tamil Nadu zone. Journal of Medicinal Plants Research. 2(12): 361-364.

Lehninger, A.L., Nelson, D.L. y Michael. M.C. 1995. Principios de Bioquímica. Segunda edición. Ediciones Omega, S.A. Barcelona, España. pp. 1-1013.

Li-Chang, L., Yue-Wen, C. y Cheng-Chun, C. 2003. Antibacterial and DPPH free radical-scavenging activities of the ethanol extract of propolis collected in Taiwan. Journal of Food and Drug Analysis. 11(4): 277-282.

Loliger, J. 1991. The use of antioxidants in foods. In: free radicals and food additives. Aruoma, O.I. y Halliwell, B., Eds. Taylor and Francis, London, UK. pp. 121– 150.

Lou, Z., Wang, H., Rao, S., Sun, J., Ma C, y Li J. 2012. p-coumaric acid kills bacteria through dual damage mechanisms. Food Control. 25: 550-554.

Martínez-Flórez, S., González-Gallego, J., Culebras, J.M. y Tuñón, M.J. 2002. Los flavonoides: propiedades y acciones antioxidantes. Revisión. Nutrición Hospitalaria. 8(6): 271-278.

Mendoza-Wilson, A.M. y Glossman-Mitnik, D. 2004. CHIH-DFT determination of the molecular structure, infrared and ultraviolet spectra of the flavonoid quercetin. Journal of Molecular Structure (Theochem) 681:71–76.

Mirzoeva, O.K., Grishanin, R.N. y Calder, P.C. 1997. Antimicrobial action of propolis and some of its components: the effects on growth, membrane potential and motility of bacteria. Microbiology Research. 152: 239–46.

Moraes, C.S., Daugsch, A., Li, H., Rhim, J.S. y Park, Y.K. 2010. Comparative antiproliferation of human prostate cancer cells by ethanolic extracts of two groups of Brazilian propolis. Ciencia y Tecnología Alimentaria. Campinas. 30(2): 539-543.

Mori, A., Nishio, C., Enoki, N., y Tawata, S. 1987. Antibacterial activity and mode of actin of plant flavonoids against Proteus vulgaris and Staphylococcus aureus. Phytochemistry. 26: 2231-2234.

Ohemeng, K.A., Schwender, C.F., Fu, K.P. y Barrett, J.F. 1993. DNA gyrase inhibitory and antibacterial activity of some flavones (1). Bioorganic and Medicinal Chemistry Letters. 3:225–30.

Orsi, R.O., Sforcin, J.M., Funari, S.R., Junior A.F. y Bankova, V. 2006. Synergistic effect of propolis and antibiotics on the S. typhi. Brazilian Journal of Microbiology. 37: 108-112.

Osawa, K., Yasuda, H., Maruyama, T., Morita, H., Takeya, K., y Itokawa, H. 1992. Isoflavanones from the heartwood of Swartzia polyphylla and their antibacterial activity against cariogenic bacteria. Chem Pharm Bull (Tokyo). 40: 2970– 2974.

Peña, R.C. 2008. Literature review: Propolis standardization: a chemical and biological review. Ciencia e Investigación Agraria. 35(1): 11-20.

Pepeljnjak, S. y Kosalec, I. 2004. Galangin expresses bactericidal activity against multiple-resistant bacteria: MRSA, Enterococcus spp. and Pseudomonas aeruginosa. FEMS Microbiology Letters. 240: 111–116.

Sagdic, O., Silici, S. y Yetim, H. 2007. Fate of Escherichia coli and E. coli O157:H7 in apple juice treated with propolis extract. Annals of Microbiology. 57(3): 345-348.

Sato, M., Fujiwara, E. y Tsuchiya. 1996. Flavones with antibacterial activity against cariogenic bacteria. Journal of Ethnopharmacology. 54: 171-176.

Sato, M., Tsuch iya, H., Akagiri, M., Takagi, N. y Iinuma, M. 1997. Growth inhibition of oral bacteria related to denture stomatitis by anti-candidal chalcones. Australian Dental J. 42: 343-346.

Shaidi, F. y Chandrasekara, A. 2010. Hydroxycinnamates and their in vitro and in vivo antioxidant activities. Phytochemistry Reviews. 9:147–170.

Simúth, J., Trnovský, J. y Jeloková, J. 1986. Inhibition of bacterial DNA-dependent RNA polymerases and restriction endonuclease by UV absorbing components from propolis. Pharmazie. 41(2), 131-132.

Takaisi-Kikuni, N.B. y Schilcher, H. 1994. Electron microscopic and microcalorimetric investigations of the possible mechanism of the antibacterial action of a defined propolis provenance. Planta Medica. 60: 222-227.

Tosi, B., Donini, A., Romagnoli, C. y Bruni, A. 1996. Antimicrobial activity of some commercial extracts of propolis prepared with different solvents. Phytotherapy Research. 10: 335-336.

Tsuchiya, H., Sato, M. y Miyazaki, T. 1996. Comparative study on the antibacterial activity of phytochemical flavanones against methicillin resistant Staphylococcus aureus. Journal of Ethnopharmacology. 50:27-34.

Velázquez, C., Navarro, M., Acosta, A., Angulo, A., Dominguez, Z., Robles, R., Robles-Zepeda, R., Lugo, E., Goycoolea, F.M., Velazquez, E.F., Astiazaran, H. y Hernández, J. 2007. Antibacterial and free-radical scavenging activities of Sonoran propolis. Journal of Applied Microbiology. 103: 1747–1756.

Yao, L.H., Jiang, Y.M., Shi, J., Tomás-Barreran, F.A., Datta, N., Sunganusong, R. y Chen, S.S. 2004. Flavonoids in food and their health benefits. Plant Foods for Human Nutrition. 59: 113–122.

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Publicado

2014-04-30

Cómo citar

Vargas-Sánchez, R. D., Torrescano-Urrutia, G. R., Mendoza-Wilson, A. M., Vallejo-Galland, B., Acedo-Félix, E., SánchezEscalante, J. J., … Sánchez-Escalante, A. (2014). MECANISMOS INVOLUCRADOS EN LA ACTIVIDAD ANTIOXIDANTE Y ANTIBACTERIANA DEL PROPÓLEOS. Biotecnia, 16(1), 32–37. https://doi.org/10.18633/bt.v16i1.31

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