MECANISMOS INVOLUCRADOS EN LA ACTIVIDAD ANTIOXIDANTE Y ANTIBACTERIANA DEL PROPÓLEOS
DOI:
https://doi.org/10.18633/bt.v16i1.31Palabras clave:
propóleos, mecanismo antioxidante, antibacteriano, flavonoides.Resumen
El propóleos es un producto elaborado por las abejas, que se caracteriza por poseer propiedades antioxidantes y antimicrobianas, las cuales son atribuidas a la presencia de compuestos polifenólicos, principalmente flavonoides. Estos compuestos son de bajo peso molecular y en su estructura química contienen un número variable de grupos hidroxilos. Varios investigadores han reportado que los mecanismos antioxidantes propuestos para estos grupos son mediante secuestro de radicales libres, o actuando como substrato para radicales, tales como superóxido e hidroxilo, y quelación de iones metálicos. Mientras que el mecanismo antimicrobiano involucra la inhibición de ácidos nucleicos y degradación de la membrana citoplasmática.Descargas
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