COMPOSICIÓN QUÍMICA DEL EXTRACTO CLOROFÓRMICO DE Scutellaria havanensis JACQ
DOI:
https://doi.org/10.18633/biotecnia.v19i3.448Keywords:
Scutellaria havanensis, flavonoides, wogonina, CG-EMAbstract
El género Scutellaria, que pertenece a la familia Lamiaceae, incluye alrededor de 350 especies. Sus extractos y compuestos, principalmente flavonoides, han mostrado propiedades anti-inflamatorias, ansiolíticas, neuroprotectoras, antitrombóticas, antidiabéticas, anticancerígenas, antioxidantes, antimicrobianas y antivirales. Scutellaria havanensis Jacq., comúnmente llamada Escudo de La Habana, es la única especie de este género que crece en Cuba. Es una hierba perenne y se utiliza en etnomedicina para el tratamiento de la escabiosis, como diaforético y febrífugo. También se cultiva con fines ornamentales. Hasta el presente se han encontrado pocos estudios químicos y farmacológicos acerca de esta planta. Teniendo en cuenta las propiedades farmacológicas reportadas para as diferentes especies de Scutellaria y sus compuestos, se llevó a cabo la caracterización por cromatografía de gases acoplada a espectrometría de masas del extracto clorofórmico de las partes aéreas de S. havanensis. Se encontró que dicho extracto estaba constituido por un 80% de flavonoides, donde la wogonina, dihidrowogonina, baicaleina, 5,2-dihidroxi-6,7,8-trimetoxiflavona y ácido crisofánico, fueron los componentes más abuntantes. Entre ellos, la wogonina fue el componente mayoritario con 48,3%.
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