Phenolic compounds, antihemolytic, anti-inflammatory and antibacterial activity of propolis from southern Sonora
DOI:
https://doi.org/10.18633/biotecnia.v24i3.1746Keywords:
Propolis, antioxidant, antimicrobial, anti-inflammatoryAbstract
Propolis is a resin made by Apis mellifera bees from vegetation exudates. Biological properties have been documented. This study evaluated the antioxidant, anti-inflammatory and antibacterial activity in ethanolic extracts of propolis from southern Sonora, Mexico. The concentration of total phenols and flavonoids was measured. Antioxidant activity was measured and antihemolytic and anti-inflammatory activity of human erythrocytes was determined. In addition, the activity against Escherichia coli O157:H7, Staphylococcus aureus and Salmonella typhimurium bacteria was evaluated. The ethanolic extracts presented concentrations of 16.36 ± 1.93 mg EAG/ge and 42.96 mg EQ/ge of phenols and flavonoids, respectively. The DPPH and ABTS radicals showed values of 75.65 ± 3.76 and 29.61 ± 0.01 mg ET/gPS respectively, the extracts protected up to 49.56% from hemolysis and prevented cell inflammation up to 49.56%. They also presented antibacterial activity against all the strains evaluated, showing inhibition halos of 8 to 11.3 mm and MIC of 1 and 2 mg of extract/mL The results are the basis for the study of natural formulations with propolis from southern Sonora.
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